4basebio (EXPEDEON AG)

Company Overview

Expedeon AG (formerly known as Sygnis AG) develops and markets products for the genomic amplification market, including unique engineered DNA polymerase enzymes marketed as part of its TruePrime amplification kits. Other products include RunBlue Electrophoresis for separating and purifying DNA or proteins, and Lightning-Link and CaptSure for labeling and immobilization of molecules for immunoassays.

A key Syngis innovation is the discovery of TruPrimPol, a novel DNA polymerase enzyme that eliminates the need for synthetic random primers. This polymerase is marketed as part of Expedeon’s TruePrime Single Cell WGA kit.

The TruePrime platform is capable of accurately and reliably amplifying a very small amount of DNA contained in a single cell (7 picograms) to more than 1 million times within three hours. This enables NGS analysis at the single-cell level and makes it useful for liquid biopsy and rare disease diagnostic applications in which tiny amounts of DNA must be analyzed.

Financial Highlights (FY 2023)

Company's Business Segments

• DNA synthesis : The company provides synthetic DNA constructs and mRNA and develops vectors for cell and tissue-specific delivery for multiple applications.