| Year | Detail |
| 1887 |
BRISTOL-MYERS SQUIBB CO. was founded as CLINTON PHARMACEUTICALS. |
| 1892 |
Dr. Squibb forms a partnership with his sons, Edward and Charles, and the firm is renamed E.R Squibb & Sons. |
| 1895 |
First breakthrough a product called Sal Hepatica salts, marketed as a tonic and laxative. |
| 1899 |
Bristol and Myers rename their business the Bristol, Myers Company, which outgrows its home in Clinton, New York. The company relocates — first to Syracuse and then, in 1899, to Brooklyn to better serve customers in New England and Pennsylvania. |
| 1901 |
Bristol-Myers introduces Ipana toothpaste, featuring a disinfectant to prevent tooth decay and gum disease. |
| 1902 |
E.R. Squibb & Sons establishes its first quality-control laboratory. |
| 1905 |
E.R. Squibb & Sons purchases an ether manufacturing plant in what was then the wilds of New Brunswick, New Jersey. |
| 1914 |
Squibb Biological Laboratories division produces antitoxins, serums and vaccines. |
| 1917 |
E.R. Squibb & Sons pioneers the standardization of digitalis, derived from the foxglove plant as an early treatment for heart conditions. |
| 1919 |
The company expands westward by opening a distribution center in Chicago, and also organizes an export department in Brooklyn. |
| 1938 |
Established Squibb Institute for Medical Research in New Brunswick, New Jersey. |
| 1943 |
Bristol-Myers acquires Cheplin Laboratories in Syracuse, New York, enabling it to mass produce penicillin during World War II. This marks the company’s entry into ethical drug development. |
| 1944 |
Squibb opens the world’s largest penicillin production facility in New Brunswick, New Jersey. |
| 1948 |
Bristol Laboratories introduces Flo-Cillin 96, a long-lasting injectable penicillin and also introduced Bufferin, a new pain reliever. |
| 1956 |
Bristol-Myers enters the cancer drug development field, building on collaborations around promising antibiotics with the Microbial Chemistry Research Foundation of Japan. |
| 1959 |
Bristol-Myers acquires the hair-coloring company Clairol, which was founded in 1931 by Joan and Lawrence M. Gelb. Their son, Richard L. Gelb. |
| 1966 |
Bristol-Myers Products research and development laboratories in Hillside, New Jersey. |
| 1967 |
Bristol-Myers acquires Mead Johnson. |
| 1971 |
Squibb establishes worldwide headquarters in Princeton, New Jersey. |
| 1974 |
Bristol Laboratories introduces cancer chemotherapy agent Blenoxane. |
| 1983 |
The FDA approves Bristol Laboratories VePesid. |
| 1989 |
Bristol-Myers merges with Squibb, creating a global leader in the health care industry. |
| 1991 |
FDA approves TAXOL. |
| 1997 |
Bristol-Myers Squibb opens a 433-acre research campus in Hopewell, New Jersey. |
| 1998 |
President Bill Clinton awards the National Medal of Technology — America’s highest honor for technological innovation — to Bristol-Myers Squibb. |
| 1999 |
The Bristol Myers Squibb Foundation announces SECURE THE FUTURE. |
| 2001 |
The Bristol-Myers Squibb Children’s Hospital opens as part of Robert Wood Johnson University Hospital in New Brunswick, New Jersey. |
| 2001 |
Acquired DuPont pharmaceuticals. |
| 2008 |
Celgene and Accerleron Pharma announce research collaboration to develop therapies for cancer and other rare diseases. |
| 2009 |
Bristol Myers Squibb acquires Medarex, Inc. |
| 2010 |
Celgene and Agios Pharmaceutical, Inc. announce global strategic collaboration focused on targeting cancer metabolism. |
| 2018 |
Celgene gains INREBIC (fedratinib) from IMPACT BioMedicines purchase. |
| 2018 |
The acquisition contributes to Celgene’s stature as a premier cellular immunotherapy. |
| 2019 |
European Commission approves combination regimen for REVLIMID (lenalidomide) and Imnovid (pomalidomide). |
| 2019 |
Bristol-Myers Squibb acquired Celgene. |
| 2020 |
Bristol Myers Squibb acquires MyoKardia. |
| 2021 |
Bristol Myers Squibb and Eisai announce global strategic collaboration for Eisai’s antibody drug conjugate. |
| 2022 |
Bristol Myers Squibb acquires Turning Point Therapeutics. |