| Year | Detail |
| 1918 |
The American Cellulose & Chemical Manufacturing Company (Amcelle) was founded in New York City, New York, USA, and later became Celanese Corp. |
| 1921 |
Celanese began commercial production of acetate yarn. |
| 1926 |
Celanese Canada was formed in Drummondville, Canada. |
| 1927 |
The American Cellulose & Chemical Manufacturing Co. changes its name to "Celanese Corporation of America." |
| 1945 |
Celanese established a production plant in Bishop, Texas. |
| 1961 |
Celanese Corp. of America and Hoechst A.G. set up the Ticona Polymerwerke joint venture in Kelsterbach, Germany. |
| 1965 |
Celanese opens a manufacturing facility in Lanaken, Belgium. |
| 1979 |
Establishment of Celanese Far East Ltd in Hong Kong, China. |
| 1981 |
Celanese, SABIC, and Duke Energy entered the Ibn Sina joint venture. |
| 1993 |
Celanese acquired Copley Pharmaceuticals Inc. |
| 2000 |
Celanese A.G. acquired the polyvinyl alcohol business from Air Products. |
| 2002 |
The company acquired European emulsions and global emulsion powders businesses from Clariant A.G. |
| 2009 |
Celanese acquired the long fiber reinforced thermoplastics (LFRT) business of FACT GmbH. |
| 2010 |
Celanese acquired two product lines from DuPont Performance Polymers: Zenite and Thermx. |
| 2013 |
Celanese and Mitsui & Co. Ltd. established a joint venture to produce methanol. |
| 2016 |
Celanese acquired SO.F.TER. |
| 2018 |
The company opened a new Customer Color & Aesthetics Solution Center in Florence, Kentucky, U.S. |
| 2022 |
Celanese completes the acquisition of the Mobility & Materials Business of DuPont. |
| 2023 |
Celanese and TracXon announced a collaboration on a large area of LED-on-Foil. |