| Year | Detail |
| 1867 |
The company was founded. |
| 1882 |
Incorporates in Missouri as Mallinckrodt Chemical Works. |
| 1884 |
Establishes its first office in New York City. |
| 1924 |
Introduced iodeikon to the scientific community. |
| 1950 |
Introduces UROKON SODIUM. |
| 1962 |
The company acquired Van Pelt & Brown. |
| 1966 |
Acquires Nuclear Consultants, Inc. of Maryland Heights, Missouri. |
| 1982 |
Avon acquired Mallinckrodt. |
| 1986 |
The company was acquired by the International Minerals and Chemical Corporation. |
| 1995 |
Launched the company's first generic pharmaceutical. |
| 2000 |
Mallinckrodt was acquired by Tyco International. |
| 2007 |
Tyco Healthcare got separated from Tyco International and renamed itself as Covidien, an independent company. |
| 2012 |
The company acquired CNS Therapeutics and its intrathecal therapy products. |
| 2015 |
The company acquired Ikaria, Inc. |
| 2019 |
The company completed the sales of wholly owned subsidiary BioVectra Inc. |
| 2021 |
Received FDA approval of StrataGraft. |
| 2022 |
Received FDA approval for Terlivaz. |
| 2024 |
The company got U.S. FDA approval for supplemental new drug application for Acthar Gel. |