| Year | Detail |
| 1988 |
Regeneron was founded. |
| 1990 |
Announced a collaboration to develop neurotrophic factors. |
| 1992 |
Clinical development of investigational drug, a neurotrophic factor, begins. |
| 2000 |
Investigational medicine rilonacept begins clinical exploration. |
| 2004 |
Investigational medicine aflibercept begins clinical development. |
| 2006 |
Entered a collaboration with Bayer HealthCare. |
| 2007 |
The company collaborated with Sanofi. |
| 2008 |
The FDA approved first medicine, ARCALYST Injection. |
| 2013 |
European business office opens in Dublin, Ireland. |
| 2015 |
Launched a major new immuno-oncology collaboration with Sanofi. |
| 2022 |
The company acquried Checkmate Pharmaceuticals. |